Timothy P. Singleton, M.D.

Associate Professor

Educational Background

• University of Minnesota, Duluth, Minnesota (1982), B.S. (Biology and Chemistry)
• University of Minnesota Medical School, Minnesota (1987), M.D.
• University of Minnesota Medical Center, Minnesota (1991), Resident (Anatomic and Clinical Pathology)
• Stanford University Medical Center, California (1992), Fellow (Surgical Pathology)
• University of Minnesota Medical Center, Minnesota (1993), Fellow (Hematopathology)

Board Certification

• Diplomate, American Board of Pathology in Anatomic and Clinical Pathology, 1993 – Present
• Diplomate, American Board of Pathology in Hematology, 1997 – Present

Professional Background

• Clinical Instructor and Staff Physician, Stanford University Medical Center, Department of Pathology, California, 1992-1994
• Assistant Director and Co-Director, University of Michigan Hospitals, Clinical Immunohistochemistry, Ann Arbor, Michigan, 1994-2000
• Assistant Professor, University of Michigan Medical School, Pathology (Hematopathology), Ann Arbor, Michigan, 1994-2000
• Chief, William Beaumont Hospital, Flow Cytometry, Royal Oak, Michigan, 2000-2004
• Director, University of Minnesota Medical Center, Fairview, Hematopathology – Flow Cytometry, Minneapolis, MN, 2004 - Present

Professional Memberships

• American Medical Association
• American Society of Hematology
• Clinical Cytometry Society
• Society for Hematopathology
• United States and Canadian Academy of Pathology 

Publications

• Elimelakh M, Dayton V, Park KS, Gruessner AC, Sutherland D, Howe RB, Reding MT, Eastlund T, van Burik JA, Singleton TP, Gruessner RW, Key NS: Red cell aplasia and autoimmune hemolytic anemia following immunosuppression with alemtuzumab, mycophenolate, and daclizumab in pancreas transplant recipients, Haematologica 2007, 92:1029-1036
• Dolan MM, Singleton TP, Neglia J, Cioc A: Aplastic anemia and monosomy 7-associated dysmegakaryocytopoiesis, Am J Clin Pathol 2006, 126:925-930
• Smith MD, Singleton TP, Balaraman S, Jaiyesimi I, O'Malley B, Al-Saadi A, Mattson JC: Case report: mantle cell lymphoma, prolymphocytoid variant, with leukostasis syndrome, Mod Pathol 2004, 17:879-883
• Chen JC, Zhang X, Singleton TP, Kiechle FL: Mitochondrial membrane potential change induced by Hoechst 33342 in myelogenous leukemia cell line HL-60, Ann Clin Lab Sci 2004, 34:458-466
• Kansal R, Ross CW, Singleton TP, Finn WG, Schnitzer B: Histopathologic features of splenic small B-cell lymphomas. A study of 42 cases with a definitive diagnosis by the World Health Organization classification, Am J Clin Pathol 2003, 120:335-347

Presentations

• V Robu and TP Singleton. Bcl−2 in Monoclonal B Cells of Reactive Follicular Hyperplasia. A Flow Cytometry Study (USCAP poster, 2008)
• Cioc AM, Singleton TP, Neglia JP, Dolan MM. Aplastic anemia may acquire monosomy 7 associated with dysthrombopoiesis. Mod Pathol 19(supplement 1):220A, 2006 (USCAP poster)
• Cioc AM, Dolan MM, and Singleton TP. Myeloid/natural killer cell precursor immunophenotype is present in heterogeneous acute leukemias. Mod Pathol 19(supplement 1):220A, 2006 (USCAP poster)
• Alvarez H, Dayton VD, Dolan MM, and Singleton TP. Atypical blast morphology at relapse of acute promyelocytic leukemia. Mod Pathol 19(supplement 1): 215A-216A, 2006 (USCAP poster)
• Johnson E, Shah N, Singleton T, Panoskaltsis-Mortari A, and Lebien TW. Re-examining the role of IL-7 in human B lymphopoiesis. Blood 106(110): 102a, 2005 (ASH platform)
• Elimelakh M, Dayton V, Park KS, Gruessner RW, Gruessner AC, Sutherland DE, Bland B, Howe RB, van Burik JA, Asraani AA, Reding MT, Singleton TP, and Key NS. Acquired pure red cell aplasia associated with alemtuzumab, mycophenolate, and daclizumab immunosuppression after pancreas transplant. Blood 106(11): 308a-309a, 2005 (ASH poster)
• Smith MD and Singleton TP. Circulating B-cells that lack surface immunoglobulin light chain usually represent lymphoma/leukemia. Modern Pathology 17(supplement 1): 271A, 2004. (USCAP poster)
• Parling-Lynch KJ, Zakalik D, Hwang R, Singleton TP, and Wong CYO. Significant differences of standard uptake values (SUV) from PET scan between indolent and aggressive lymphomas. Blood 102(11, part 2):270b, 2003. (ASH)
• Smith MD, Mattson JC and Singleton TP. Acute bilineal leukemia, B-precursor lymphoblastic and monocytic, with del (11)(q23). (Society for Hematopathology and the European Association for Hematopathology 2003 Workshop, Memphis, TN.)
• Smith MD, Mattson JC and Singleton TP. Acute promyelocytic leukemia. (Society for Hematopathology and the European Association for Hematopathology 2003 Workshop, Memphis, TN.)
• Chen JC and Singleton T. Quantitation of Platelet Associated Immunoglobulin by Antibody Binding Capacity. (Great Lakes International Imaging and Flow Cytometry Association Meeting, Milwaukee, Wisconsin, 2003.)
• Selby D, Padmore R, Tuck M, Ross C, Schnitzer B, Finn W, Valdez R, Singleton T, and Kaminski M. Characterization of Bone Marrow Lymphoid Aggregates in Follicular Lymphoma Treated with [131I] Anti-B1 Antibody. Mod Pathol 16(1):251A, 2003. (USCAP)