David H. McKenna, Jr., M.D.

Assistant Professor
612-624-5736
mcken020@umn.edu

Dr. McKenna is Assistant Professor of Laboratory Medicine and Pathology and Assistant Medical Director of the Clinical Cell Therapy Lab at the University of Minnesota Medical Center, Fairview and the American Red Cross Cord Blood Program.  He is actively involved with the NHLBI-sponsored PACT (Production Assistance for Cellular Therapy) group, as the University of Minnesota was recently designated as one of three national somatic cell processing sites. 

Educational Background

• University of Notre Dame, B.S.
• Saint Louis University School of Medicine, M.D.
• University of Minnesota, Residency (Laboratory Medicine and Pathology)
• University of Minnesota, Fellowship (Transfusion Medicine, with emphasis on Cellular Therapy)

Memberships in Professional/Academic Organizations

• International Society for Cellular Therapy, Member
• BEST Collaborative, Cellular Therapy Team, Associate Scientific Member
• American Society of Hematology, Member
• American Association of Blood Banks, Member
• Academy of Clinical Laboratory Physicians and Scientists, Associate Member

Committees

• Co-chair, Education Committee, Production Assistance for Cellular Therapies (PACT), an NHLBI-sponsored initiative
• Member, Lab Practices Committee, International Society for Cellular Therapy

Research Interests

Dr. McKenna’s research interests include umbilical cord blood research, QA/QC in cellular therapy, and translational research/clinical scale-up of biotherapeutics.

Selected Publications

• McKenna D, Rupp C, Wagner J, McGlennen R, Hirsch B, Dolan M, Burger S, Hanson M, Jaszcz W, Nguyen P. Increased lymphoblast-like cells following umbilical cord blood stem cell transplantation do not predict recurrent acute leukemia. Leukemia 2002; 16:2171-72.
• McKenna D, Kadidlo D, Sumstad D, McCullough J.  Development and operation of a quality assurance system for deviations from standard operating procedures in a clinical cell therapy laboratory. Cytotherapy 2003; 5(4):314-22.
• Chrysler G, McKenna D, Schierman T, Kadidlo D, Askari S, Miller J, Clay M, McCullough J. Umbilical cord blood banking. In: Broxmeyer HE, editor. Cellular characteristics of cord blood and cord blood transplantation. 2nd ed., Bethesda, MD, AABB Press, 2004.
• McKenna D and Clay M. Hematopoietic stem cell processing and storage. In: Murphy M and Pamphilon D, editors. Practical transfusion medicine. 2nd ed., Oxford, UK, Blackwell Publishing Ltd., 2005.
• McCullough J, McKenna D, Kadidlo D, Schierman T, Wagner J. Issues in the quality of umbilical cord blood stem cells for transplantation. Transfusion 2005; 45: 832-841
• Miller JS, Soignier Y, Panoskaltsis-Mortari A, McNearny S, Yun G, Fautsch S, McKenna D, Le C, DeFor T, Burns L, Orchard P, Blazar BR, Slungaard A, Weisdorf D, Okazaki I, McGlave PB. Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in cancer patients. Blood 2005; 105 (8): 3051-3057.
• McKenna D, Kadidlo D, Miller J, Orchard P, Wagner J, McCullough J. The Minnesota Molecular & Cellular Therapeutics Facility: a state-of-the-art biotherapeutics engineering laboratory. Transfusion Medicine Reviews 2005; 19(3): 217-228.