David H. Maurer, Ph.D., dABHI - MED - Laboratory Medicine and Pathology, University of Minnesota
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  Home > About Lab Medicine and Pathology > Faculty and Staff > David H. Maurer, Ph.D., dABHI
 

David H. Maurer, Ph.D., dABHI

Associate Professor
612-273-3131
maure077@umn.edu

PRESENT POSITIONS:
Director
Immunology/Histocompatibility Labs
University of Minnesota Medical Center
Associate Professor
Dept. of Lab. Med. & Pathology
University of Minnesota Medical School
HLA Laboratory Director
OU Medical Center
Clinical Associate Professor
Dept. of Pathology,
Coll. of Medicine
Univ. of Oklahoma Health Sci. Ctr.
MAILING ADDRESS:
(MN) Immunology Lab, Rm MMC 724
420 Delaware St. SE
Minneapolis, MN  55455
(OK) Everett Tower, Suite EB-400
1200 Everett Dr.
Oklahoma City, OK  73104
CONTACT INFO.:
Telephone:    (MN) 612-273-3131
Fax:              (MN) 612-273-7036
E-mail:          (MN) maure077@umn.edu
(OK) 405-271-2650
(OK) 405-271-7332
(OK) david-maurer@ouhsc.edu
EDUCATION:
1973-1977  Cornell University, College of Arts and Sciences, Ithaca, NY
B.A.,  Major:  Biology Concentration:  Biochemistry,
Molecular and Cell Biology
Undergraduate Advisor:  Jane Gibson, Ph.D.
1980-1987 Cornell University, Graduate School of Medical Sciences,
Sloan-Kettering Division, New York, NY
Ph.D, Field:  Immunology
 Ph.D. Advisor:  Marilyn S. Pollack, Ph.D.
POSTGRADUATE TRAINING:
3/88-1/92  Postdoctoral Research Fellow, Molecular Genetics Section (Jack Gorski, Ph.D., David Eckels, Ph.D.), Blood Center of Southeastern Wisconsin, Milwaukee, WI.
Summer 1990  F.E.B.S. International Summer School on Immunology, Spetsai, Greece
PROFESSIONAL EXPERIENCE:
1/92-8/92 Assistant Investigator, Immunogenetics Research Section, The Blood Research Institute, Blood Center of Southeastern Wisconsin, Milwaukee, WI
9/92-8/98 Assistant Professor, Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA
9/94-8/98 Director, Molecular Immunogenetics Laboratory, Medical Staff Member, Emory University Hospital, Atlanta, GA.  Established & directed new laboratory service and served as Clinical Consultant to the Matched Unrelated Donor Bone Marrow Transplant Program, Emory University Hospital
9/98-12/00 Clinical Laboratory Director, Immunological Associates of Denver, Inc., Denver, CO
10/00-6/01  Search Strategy Consultant, National Marrow Donor Program
2/01-10/05 Instructor, Department of Medicine, Division of Allergy & Clinical Immunology,  University of Colorado School of Medicine, Denver, CO
2/01-10/05 Associate Director, ClinImmune Labs, University of Colorado Health Sciences Center, Denver, CO
7/03-10/05 Technical Director, University of Colorado Cord Blood Bank, University of Colorado Health Sciences Center, Denver, CO
11/05-11/06 Associate Professor, Department of Pathology, College of Medicine, University of Oklahoma Health Sciences Center. Oklahoma City, OK
12/06-Present Associate Professor, Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis MN
12/06-Present Clinical Associate Professor, Department of Pathology, College of Medicine, University of Oklahoma Health Sciences Center. Oklahoma City, OK
1/06-Present Director, HLA Laboratory, Department of Pathology & Laboratory Services, OU Medical Center, Oklahoma City, OK
2/07-Present Co-Director, Immunology/Histocompatibility Laboratories, University of Minnesota Medical Center, Minneapolis, MN
   
EXPERT WITNESS TESTIMONY for Paternity DNA Evidence:
Specific Court
14th Judicial Court of the State of Colorado
10th Judicial Court of the State of Colorado
Court Case No.
98CR84
99CR1282 Div.8
Date
July 22, 1999
July 20, 2000
AWARDS AND SUPPORT:
Principal Investigator, National Marrow Donor Program Subcontract #7205, HLA Class I Typing using DNA-based Techniques
1998-1999 Principal Investigator, National Marrow Donor Program Subcontract #8267, HLA Class II Typing using DNA-based Techniques
2000 Principal Investigator, National Marrow Donor Program Subcontract #9009, HLA Class II Typing using DNA-based Techniques
   
BOARD CERTIFIED: Diplomate, American Board of Histocompatibility & Immunogenetics (ABHI), Examination date:  10/94
SOCIETY MEMBERSHIPS:
1992-present

American Society for Histocompatibility and Immunogenetics (ASHI)
2004-present American Association of Blood Banks
COMMITTEE MEMBERSHIPS:
1995-1999 College of American Pathologists (CAP)/American Society for Histocompatibility & Immunogenetics (ASHI) Joint Histocompatibility Testing Committee
1997-1999 Co-Chairman, CAP/ASHI Joint Histocompatibility Testing Committee
1997-1999 ASHI Quality Assurance/Standards Committee
1997-1999 ASHI Finance Committee
1997-1999 American Board of Histocompatibility and Immunogenetics (ABHI) Laboratory Director Examination Committee
FORMAL TEACHING:
1992-1998 Lecturer, Clinical Pathology Resident Lecture Series
1993, 1995 Lecturer, Molecular Pathology
1997 Didactic Summer Course
1996, 1997 Lecturer, American Red Cross SBB Student Lecture Series
SUPERVISORY TEACHING:
1993-1995 HLA Laboratory Director Training Program (ASHI-accredited). Post-doctoral trainee:  Jeffrey M. McCormack, Ph.D.
INVITED LECTURES:
September 1995 South-Eastern Organ Procurement Foundation (SEOPF) Laboratory Director’s Review Workshop
Presentation:  DNA Methodologies
May 1996 SEOPF Tri-Annual Meeting
Presentation:  Molecular Biology of HLA DNA Typing
March 1997 ASHI Southeastern Regional Education Workshop
Presentation:  Molecular HLA Typing Methods: HLA Class I
April 1998 ASHI Southern Regional Educational Workshop
Presentation:  DNA Chips: The Future of HLA Typing?
January 1999 SEOPF Tri-Annual Meeting
Presentation:  DNA Chips: The Future of HLA Technology
May 2001 Current Topics in Histocompatibility and Transplantation for Technologists
Presentation:  Donor Search Strategies
October 2001 AABB Annual Meeting
Presentation:  Strategies for HLA Typing for Donor Selection for Bone Marrow, Peripheral Blood, and Cord Blood Stem Cell Transplantation
October 2002 AABB Annual Meeting
Presentation:  Donor Selection Strategies for Unrelated Hematopoietic Stem Cell Transplantation

BIBLIOGRAPHY:

PUBLISHED ARTICLES IN REFEREED JOURNALS:

1.          Pollack, M.S., D. Maurer, L.S. Levine, M.I. New, S. Pang, H.M. Nitowsky, G. Sachs, M. Duchon, I.  Merkatz, R.P. Owens and B. Dupont.  1979.  Prenatal diagnosis of congenital adrenal hyperplasia (21?hydroxylase deficiency) by HLA typing.  Lancet 1:1107.

2.         Pollack, M.S., D. Maurer , L.S. Levine, M.I. New, et al.  1979.  HLA typing of amniotic cells:  The prenatal diagnosis of congenital adrenal hyperplasia (21?OH deficiency type).  Transplant. Proc. 11:1726.

3.        Maurer, D.H., K. Welte, R. Mertelsmann, M.A.S. Moore and P. Ralph.  1983.  Lymphokine factors inducing IgG production in human B cell line ARH?77 and stimulatory effects of phorbol ester tumor promoter.  Cell. Immunol. 79:36.

4.         Ralph, P., O. Saiki, D.H. Maurer and K. Welte.  1983.  IgM and IgG secretion in human B cell lines regulated by B cell inducing factors (BIF) and phorbol ester.  Immunol. Lett. 7:17.

5.         Mattes, M.J., M. Tanimoto, M.S. Pollack and D.H. Maurer.  1983.  Preparing monolayers of non?adherent mammalian cells.  J. Immunol. Methods 61:145.

6.         Pollack, M.S., D.H. Maurer, M.J. Mattes, D. LeBlanc, S.D. Horowitz and R. Hong.  1983.  HLA typing of amniotic fluid cells for the determination of therapeutic transplantation options for a fetus affected with ADA deficiency.  Transplantation 36:336.

7.         Maurer, D.H., W.E. Collins, J.H. Hanke, M. Van, R.R. Rich and M.S. Pollack.  1985.  Class II positive human dermal fibroblasts restimulate cloned allospecific T cells but fail to stimulate primary allogeneic lymphoproliferation.  Hum. Immunol. 14:245.

8.         Callaway, C., C. Falcon, G. Grant, D.H. Maurer, A.D. Auerbach, Z. Rosenwaks and M.S. Pollack.  1986.  HLA typing used with cultured amniotic and chorionic   villus cells for early prenatal diagnosis or parentage testing without one parent's availability.  Hum. Immunol. 16:200.

9.         Maurer, D.H., K. Baker, C.V. Sumaya, D. Brown, C. Callaway and M.S. Pollack.  1986.  The use of Epstein?Barr virus transformation for the establishment of class II positive cord blood cells for use in analysis of maternal sera.  Tissue Antigens 28:24.

10.        Callaway, C., D.H. Maurer, D. Brown, W. Fang, K.M. Fehir, M.S. Pollack.  1986.  The use of phytohemagglutinin?stimulated mononuclear cell subpopulations for HLA typing studies involving chronic myelogenous leukemia patients.  Transplantation 42:315.

11.        Maurer, D.H., J.H. Hanke, E. Mickelson, R.R. Rich and M.S. Pollack.  1987.  Differential presentation of HLA?DR, DQ and DP restriction elements by interferon?gamma?related dermal fibroblasts.  J. Immunol. 139:715.

12.        Maurer, D.H., C. Callaway, S. Sorkin and M.S. Pollack.  1987.  Gamma?interferon induces detectable serological and functional expression of DR and DP but not DQ antigens on cultured amniotic fluid cells.  Tissue Antigens 31:174.

13.        Pollack, M.S., C. Callaway and D.H. Maurer.  1988.  Prenatal diagnosis of 21-hydroxylase deficiency.  Prenat. Diagn. 8:245.

14.        Pollack, M.S., C. Callaway, S. Sorkin, A. Zaafran and D. Maurer.  1989.  Differential induction of class I and class II HLA molecules on cultured amniotic fluid and chorionic villus cells by gamma?interferon.  Transplantation Proceedings 21:635.

15.        Maurer, D. and J. Gorski.  1991.  Transfer of polymorphic monoclonal antibody epitopes to the first and second domains of HLA-DR b-chains by site-directed mutagenesis.  J. Immunol. 146:621.

16.       Gramlich, T., C. Fritsch, D. Maurer, M. Eberle, and T. Gansler.  1994. Differential polymerase chain reaction assay of cyclin D1 gene amplification in esophageal carcinoma.  Diagnostic Molecular Pathology 3:255.

17.       Williams, T. M., S. Bassinger, C. Moehlenkamp, J. Wu, G. D. Montoya, B. B. Griffith, J. D. McAuley, S. Goldman, D. H. Maurer and G. M. Troup. 1996.  Strategy for distinguishing a new DQB1 allele (DQB1*0611) from the closely related DQB1*0602 allele via sequence specific PCR or direct DNA sequencing.  Tissue Antigens 48(3):143.

18.        Geller, R.B., S. Devine, K. O’Toole, L. Person, J. Keller, D. Maurer, K. H.  Holland, S.  Dix, M.. Piotti, S. Redei, G. Connaghan, L. T. Heffner, C. Hillyer, E. Winton and J. Wingard.  1997.  Allogeneic bone marrow transplantation with matched unrelated donors for patients with hematopoietic malignancies using a preparative regimen of high-dose cyclophosphamide and fractionated TBI.  Bone Marrow Transplantation 20(3):219?25, 1997.

19.        Devine, Steven M., Robert B. Geller, Lillian B. Lin, Suzanne P. Dix, H. Kent Holland, David Maurer, Kathleen O’Toole, James Keller, Daniel G. Connaghan, Leonard T. Heffner, Christopher D. Hillyer, Glenn E. Rodey, Elliott F. Winton, Rochelle M. Maher, William E. Fitzsimmons and John R. Wingard.  1997.  The Outcome of Unrelated Donor Bone Marrow Transplantation in Patients with Hematologic Malignancies Using Tacrolimus (FK506) and Low Dose Methotrexate for Graft-Versus-Host Disease Prophylaxis.  Biology of Blood & Marrow Transplantation 3:25-33.

20.       Elwood, Eric T., Christian P. Larsen, David H. Maurer, Kristine L. Routenberg, John F. Neylan, John D. Whelchel, David P. O’Brien, Thomas C. Pearson.  1997.  Microchimerism and Rejection in Clinical Transplantation: Methodology Revisited.  The Lancet 349(9062):1358-60.

21.        McCormack, Jeffrey M., Martha Sherman, David Maurer.  1997.  Quality Control for DNA Contamination in Laboratories Using PCR-Based Class II HLA Typing Methods.  Human Immunology 54:82-88.

22.       Maiers, Martin, Carolyn Katovich Hurley, Lorah Perlee, Marcelo Fernandez-Vina, Jeanine Baisch, Daniel Cook, Patricia Fraser, Uwe Heine, Susan Hsu, Mary Sue Lefell, David Maurer, Harriet Noreen, Ting Tang, Massimo Trucco, Soo Young Yang, Neng Yu, Robert J. Hartzman, Michelle Setterholm, Tamara Winden, Devan Shepard, Janet Hegland.  2000.  Maintaining updated DNA-based HLA assignments in the National Marrow Donor Program bone marrow registry.  Reviews in Immunogenetics 2(4):449.

23.       Adamkiewicz TV, Mehta PS, Boyer MW, Kedar A, Olson TA, Olson E, Chiang KY, Maurer D, Mogul MJ, Wingard JR, Yeager AM.  2004.  Transplantation of unrelated placental blood cells in children with high-risk sickle cell disease.  Bone Marrow Transplant. 2004.  34(5):405.


BOOK CHAPTERS:

1.          Maurer, D.H. and M.S. Pollack.  The use of gamma interferon to increase HLA antigen expression on cultured amniotic cells used for the prenatal diagnosis of 21-hydroxylase deficiency.  In Symposium on Congenital Adrenal Hyperplasia.  M.I. New, and B. Dupont, eds.  Ann. N.Y. Acad. Sci. 458:148.  1985. 

2.         Maurer,D.H. and M.S. Pollack.  Analysis of defective class II allo-stimulation by gamma-interferon activated fibroblasts.  In Immunobiology of HLA, Vol. II.  Dupont B, ed., Springer-Verlag, 1989.

3.         Maurer,D., A. Madrigal and J. Gorski.  Thr77 controls a public xeno-antibody epitope on HLA-DRB1.  In HLA 1991, Vol.2.  K. Tsuji, M. Aizawa, and T. Sasazuki, eds.  Oxford University Press, Oxford.  p. 404.

4.         Newton-Nash, D.K., D. Maurer, D., J. Gorski and D.D. Eckels.  Peptide involvement in formation of the HLA-DR1 allo-epitope.  In HLA 1991, Vol.2.  K. Tsuji, M. Aizawa, and T. Sasazuki, eds.  Oxford University Press, Oxford.  p. 580.

5.         McGinnis, M., C. Brown, R. Chadwick, M. Conrad, M. Kronick, D. Ivannisci, D. Bellissimo, D. Maurer, N. Larsen, J. Wu, T. Williams, V. Schaeffer, D. Charron, A.W. van der Zwan, E. Rozemuller, and M.G.J. Tilanus.  Multi-site validation of DRB region sequencing based typing using the 12th International Histocompatibility Workshop panel.  In HLA, Genetic diversity of HLA Functional and Medical Implication, Vol.1.  Charron, D., ed..  EDK Medical and Scientific International Publisher, Paris.  p. 238. 1997.

 

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