H. Evin Gulbahce, M.D.

Associate Professor

Educational Background

• Hacettepe University Faculty of Medicine, Ankara, Turkey (1988), M.D.
• Ankara University (1990), Residency (Pathology)
• University of Pittsburgh (1992), Graduate Student/Research Assistant (Pathology)
• University of Minnesota (1996), Residency (Pathology)
• University of Minnesota (1997), Fellowship (Surgical Pathology)
• University of Minnesota (1998), Research Fellowship

Professional Background

• Instructor, University of Minnesota Medical School, Department of Laboratory Medicine and Pathology, 1998 - 1999
• Assistant Professor and Co-Director of Anatomic Pathology Research Lab, University of Minnesota Medical School, Department of Laboratory Medicine and Pathology, 1999 - present

Publications

• Alsharif M, Cameron SE, Young JA, Savik K, Henriksen JC, Gulbahce HE, Pambuccian SE. Time trends in fungal infections as a cause of death in hematopoietic stem cell transplant recipients: an autopsy study. Am J Clin Pathol. 2009 Nov;132(5):746-55.
• Varghese L, Ngae MY, Wilson AP, Crowder CD, Gulbahce HE, Pambuccian SE. Diagnosis of metastatic pancreatic mesenchymal tumors by endoscopic ultrasound-guided fine-needle aspiration. Diagn Cytopathol. 2009 May 20.
• Alsharif M, Kjeldahl K, Curran C, Miller S, Gulbahce HE, Pambuccian SE. Clinical significance of the diagnosis of low-grade squamous intraepithelial lesion, cannot exclude high-grade squamous intraepithelial lesion. Cancer Cytopathol. 2009 Apr 25;117(2):92-100.
• Alsharif M, McKeon DM, Gulbahce HE, Savik K, Pambuccian SE. Unsatisfactory SurePath liquid-based Papanicolaou tests: causes and significance. Cancer Cytopathol. 2009 Feb 25;117(1):15-26.
• Schmidt JL, Henriksen JC, McKeon DM, Savik K, Gulbahce HE, Pambuccian SE. Visual estimates of nucleus-to-nucleus ratios: can we trust our eyes to use the Bethesda ASCUS and LSIL size criteria? Cancer. 2008 Oct 25;114(5):287-93.
• Alsharif M, Aslan DL, Jessurun J, Gulbahce HE, Pambuccian SE. Cytologic diagnosis of metastatic seminoma to the prostate and urinary bladder: a case report. Diagn Cytopathol. 2008 Oct;36(10):734-8.
• Thrall MJ, Pambuccian SE, Stelow EB, McKeon DM, Miller L, Savik K, Gulbahce HE. Impact of the more restrictive definition of atypical squamous cells introduced by the 2001 Bethesda System on the sensitivity and specificity of the Papanicolaou test: a 5-year follow-up study of Papanicolaou tests originally interpreted as ASCUS, reclassified according to Bethesda 2001 criteria. Cancer. 2008 Jun 25;114(3):171-9.
• Thrall M, Kjeldahl K, Savik K, Gulbahce HE, Pambuccian SE. Rate of endometrial adenocarcinoma in women screened before and after implementation of the Bethesda 2001 reporting system. Acta Cytol. 2008 Jan-Feb;52(1):1-7.
• Aslan DL, Pambuccian SE, Prekker FL, Schacker TW, Southern P, Savik K, McKeon D, Gulbahce HE. Accuracy of herpes simplex virus detection in liquid-based (SurePath) Papanicolaou tests: a comparison with polymerase chain reaction. Diagn Cytopathol. 2008 Feb;36(2):94-103.
• Thrall MJ, Kjeldahl KS, Savik K, Gulbahce HE, Pambuccian SE. Liquid-Based Pap Test (SurePath) Interpretations Prior to the Histologic Diagnosis of Endometrial Hyperplasia and Carcinomas: A Study of 272 Cases Classified by the 2001 Bethesda System. Cancer Cytopathology 2007, 111(4):217-23
• Woon CS, Pambuccian SE, Lai R, Jessurun J, Gulbahce HE. Ciliated Foregut Cyst of Pancreas: Cytologic Findings on Endoscopic Ultrasound Guided Fine Needle Aspiration. Diagnostic Cytopathology 2007, 35(7):433-8
• Thrall MJ, Kjeldahl KS, Savik K, Gulbahce HE, Pambuccian SE. The Rate of Discovery of Endometrial Adenocarcinoma in a Population of Women Undergoing Papanicolaou Test Screening Before and After the Implementataion of the Bethesda 2001 Reporting System. Acta Cytologica 2006
• Aslan DL, Prekker FL, Gulbahce HE, Schacker TW, Southern P, Savik K, McKeon D, Pambuccian SE. Accuracy of Herpes Simplex Virus Dtection in Liquid-Based (SurePath) Papanicolaou Tests: A Comparison with Polymerase Chain Reaction. Diganostic Cytopathology 2007
• Ryan LJ, Pambuccian SE, Lai R, Gulbahce HE. Endoscopic ultrasound-guided fine needle aspiration diagnosis of metastatic sex cord tumor with annular tubules: a case report. Diagn Cytopathol. 2006 Aug;34(8):576-9
• Khan K, Schwarzenberg SJ, Sharp H, Jessurun J, Gulbahce HE, Defor T, Nagarajan R. Diagnostic Endoscopy in Children Ater Hemopoietic Stem Cell Transplantation. Gastrointest Endosc. 2006 Sep;64(3):379-85
• Hart C, Opperman DA, Gulbahce E, Adams G. Branchial Cleft Cyst: A Rare Diagnosis in a 91-year-old Patient. Otolaryngol Head Neck Surg. 2006 Dec;135(6):955-7
• Oktay MF, Cureoglu S, Schachern PA, Gulbahce E, Paparella MM, Hyasi H. Histologic Changes in the Anterior Mallear Ligament and the Head of the Malleus in Otosclerosis. Otolaryngology Head and Neck Surgery. 2006 Feb; 134(2):232-5
• Aslan DL, Pambuccian SE, Gulbahce HE, Tran ML, Manivel JC. Prostatic Glands and Urothelial Epithelium in a Seminal Vesicle Cyst: Report of a Case and Review of Pathologic Features and Prostatic Ectopy. Archives of Pathology and Laboratory Meidicne. 2006 Feb;130(2):184-7
• Stelow EB, Woon C, Pambuccian SE, Thrall M, Stanley MW, Lai R, Mallery S, Gulbahce HE. Fine-needle Aspiration Cytology of Pancreatic Somatostatinoma: The Importance of Immunohistochemistry for the Cytologic Diagnosis of Pancreatic Endocrine Neoplasms. Diagnostic Cytopathology 2005 Aug;33(2):100-5.
• Stelow EB, Bardales RH, Crary GS, Gulbahce HE, W Stanley M, Savik K, E Pambuccian S. Interobserver variability in thyroid fine-needle aspiration interpretation of lesions showing predominantly colloid and follicular groups. American Journal of Clinical Patholology 2005 Aug;124(2):239-44.
• Thrall M, Kjeldahl, Savik K, Gulbahce HE, Pambuccian SE. Significance of Benign Endometrial Cells in Papanicolaou Tests from Women Aged>40Years. Cancer Cytopathology 2005 Aug 25;105(4):207-16.
• Roychowdhury M, Pambuccian SE, Aslan DL, Jessurun J, Rose AG, Manivel JC, Gulbahce HE. Pulmonary Complications after Bone Marrow Transplantation: An Autopsy Study from a Large Bone Marrow Transplantation Center. Archives of Pathology and Laboratory Medicine 2005 Mar;129(3):366-71.
• Aslan DL, McKeon DM, Stelow E, Gulbahce HE, Kjeldahl K, Pambuccian SE. Morphologic Characteristics of Trichomonas vaginalis in SUREPATH Pap Tests. Diagnostic Cytopathology Diagnostic Cytopatholology 2005 32(5):253-259.
• Stelow EB, Bardales RH, Crary G, Gulbahce HE, Stanley MW, Savik K, Pambuccian SE. Inter-observer Variabilty in Thyroid Fine Needle Aspiration Interpretation of Lesions Showing Predominantly Colloid and Follicular Groups. American Journal of Clinical Pathology 2005 Aug;124(2):239-44.
• Aslan DL, Oprea GM, Jagush S, Gulbahce HE, Pambuccian SE. C-kit (CD117) Expression in Adenoid Cystic Carcinomas does not have an Impact on Local and Distant Tumor Recurrance. Head and Neck 2005 Dec;27(12):1028-34.
• Aslan DL, Gulbahce HE, Stelow E, Setty S, Charlotte Brown, McGlennen RC, Pambuccian SE. Polymerase Chain Reaction Based Trichomonas Vaginalis Detection In Residual Surepath Samples Confirms the Accuracy of The Morphologic Diagnosis of Tv in Surepath Pap Tests. Diagnostic Cytopathology 2005 32(6):341-344.
• Aslan DL, Gulbahce HE, Pambuccian SE, Manivel JC, Jessurun J. Ki-67 Immunoreactivity in the Differential Diagnosis of Pulmonary Neuroendocrine Neoplasms in Specimens with Extensive Crush Artifact. American Journal of Clinical Pathology 2005;123(6): 874-8.
• Peters A, Manivel JC, Dolan M, Gulbahce HE, Baker KS and Verneris MR. Pulmonary Cytolytic Thrombi After Allogeneic Hematopoietic Cell Transplantation: A Further Histological Description. Biology of Blood and Marrow Transplantation 2005 June;11(6):484-5.
• Kushen M, Gulbahce HE, Lam CH. Ewing’s sarcoma of the cavernous sinus: Case report. Neurosurgery 2005 Jun;56(6):1375.
• Stelow EB, Gulbahce HE, Kjeldahl K, Oprea GM, Savik K, Pambuccian SE. Interpretive yields of screening Pap tests and diagnostic Pap tests. Diagnostic Cytopathol. 2004 Dec;31(6):427-9
• Meisamy S, Bolan PJ, Baker EH, Bliss RL, Gulbahce E, Everson LI, Nelson MT, Emory TH, Tuttle TM, Yee D, Garwood M. Neoadjuvant chemotherapy of locally advanced breast cancer: predicting response with in vivo (1)H MR spectroscopy--a pilot study at 4 T. Radiology. 2004 Nov;233(2):424-31.
• Gulbahce HE, Pambuccian SE, Jessurun J, Woodard P, Steiner ME, Manivel JC, Hite S, Ramsay RKC, Baker KS. Pulmonary Nodular Lesions in Post Bone Marrow Transplant Patients: Impact of Histologic Diagnosis on Patient Management and Prognosis. American Journal of Clinical Pathology 2004;121:205-210.
• Tun Jie, James V. Harmon Jr., H. Evin Gulbahce, Rainer Gruessner. Intraductal Papillary Mucinous Tumor of the Native Pancreas in a Pancreas-Kidney Transplant Recipient. Pancreas. 2004 May;28(4):446-9.
• Gulbahce HE, Baker SK, Kumar P, Kjeldahl K, Pambuccian SE. Atypical Cells in Bronchoalveolar Lavage Specimens from Bone Marrow Transplant Patients: A Potential Pitfall. American Journal of Clinical Pathology 2003;120:101-106.
• Gulbahce HE, Brown CA, Wick M, Segall M, Jessurun J. Graft versus Host Disease After Solid Organ Transplant. American Journal of Clinical Pathology 2003; 119:568-73.

Presentations

• Blair C, Gulbahce HE, Coles BF, Wolff RK, Sweeney C. Cyclophosphamide Metabolizing Enzyme Gene Polymorphisms and Breast Carcer Survival. Poster presentation at the American Association for Cancer Research, Los Angeles April 2007.
• Vanderwerf S, Varghese L, Sweeney C, Blair C, Gulbahce E. Lobulitis in Non Neoplastic Breast Tissue from Breast Cancer Patients Is Associated with Phenotypes That Are Commonly Seen in Hereditary Breast Cancer. Laboratory Investigation 2007; 87(suppl), 52A.
• Varghese L, Vanderwerf S, Sweeney C, C Blair C, Forster C, Gulbahce E. Chromosome 17 Polysomy Is Common in Breast Cancer Metastases and Does Not Correlate with HER2/neu Amplification or HER2/neu 2+ Staining by Immunohistochemistry. Laboratory Investigation 2007; 87(suppl), 52A.
• Varghese L, McIntosh A, Presthus J, Forster C, Zhang Y, Gulbahce HE. Do Apoptotic and Proliferative Markers Help Predict the Response to Systemic Therapy in Locally Advanced Breast Cancers? Modern Pathology 2006; 19(1):44A.
• Hart-Gouleau S, Yee D, Tuttle T, Roychowdhury M, Lee C, Aslan D, Pambuccian S, Gulbahce E. Axillary Lymph Node Dissection(ALND) in Patients with Positive Sentinel Lymph Node(SLN): Is It Needed? Modern Pathology 2005; 18(1):35A.
• Gulbahce HE, Savik K, Stelow EB, Kjeldahl K, Brown CA, Setty S, Pambuccian SE. Is Repeat PCR-Based HPV Testing for Persistent ASC -US Useful? Modern Pathology 2004; 17(1):68A.
• Roychowdhury M, Pambuccian SE, Aslan DL, Jessurun J, Rose AG, Manivel JC, Gulbahce HE. Pulmonary Complications after Bone Marrow Transplantation (BMT): An Autopsy Study from a Large BMT Center. Modern Pathology 2004; 17(1):9A.
• Aslan D.L., Warren K.U., Meisamy S., Bolan P.J., Garwood M., Yee D., Tuttle T.M., Pambuccian S.E., Gulbahce H.E. Proliferation markers predict response to neoadjuvant chemotherapy in locally advanced breast cancer which correlates with magnetic resonance imaging and magnetic resonance spectroscopy findings. ASCP Fall Meeting Sept 18-21, 2003, New Orleans.
• Gulbahce HE, Setty S, Brown CA, Warren KU, Kjeldahl K, Rohlander J, Pambuccian SE. Women Over 50 with a Diagnosis of ASCUS on Surepath Pap Tests are Unlikely to be HPV-Positive by PCR Testing and When Positive, Harbor Unusual HPV Types. Modern Pathology 2003; 16(1):66A.
• Pambuccian S, Lundeen S, Woronzoff K, Rohlander J, Kjeldahl K, Curran C, McGlennen R, Gulbahce HE. Reflex HPV Testing of ASCUS Patients: Initial Experience with PCR-Based HPV Identification and Typing. Acta Cytologica 2002 46(5):921-922.
• Skubitz AP, Trussoni D, Bowell S, Erickson K, Brown B, Kataria S, and Gulbahce HE. Quality Control Standards for Human Tissues used in Gene Expression Experiments International Society of Biological and Environmental Repositories 2002 Meeting.
• Gulbahce HE, Nguyen C, Repka T, Nguyen P, Manivel JC, Pambuccian SE. Detection of Micrometastases in Bone Marrow Biopsies of Breast Cancer Patients. Is cytokeratin Staining an Effective Way of Identifying High Risk Patients? Modern Pathology 2002; 15(1):35A.
• Gulbahce HE, Baker, KS, Kumar P, Kjeldahl K, Ramsay NKC, Pambuccian SE. Atypical Cells in Bronchoalveolar Lavage Specimens from Bone Marrow Transplant Patients: A Potential Pitfall. Modern Pathology 2002; 15(1):74A.
• Pambuccian SE, Kjeldahl KS, Gulbahce HE, Stelow HE. Autocyte PREP Increases the Positive Predictive Value for Atypical Glandular Cells of Undetermined Significance (AGUS) Diagnoses in Cervico-Vaginal Cytologic Specimens. Modern Pathology 2002; 15(1):84A.
• Gulbahce HE, Dolan M, Jessurun J, Wick M, Wijkstrom M, Kandaswamy R, Segall M, McGlennen R. Gastrointestinal Graft Versus Host Disease after Solid Organ Transplant: An Underdiagnosed Potentially Lethal Disease. Modern Pathology 2002; 15(1):128A.