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  Home > About Lab Medicine and Pathology > Faculty and Staff > Amy Skubitz, Ph.D.
 

Amy Skubitz, Ph.D.


MEDPATHOLOGY Amy Skubitz - Portrait
Contact Information

Phone: 612-625-5920
Fax: 612-625-1121

Email:

skubi002@umn.edu

Address:

MMC 609 Mayo
8609
420 Delaware
Minneapolis, MN 55455




Professor

Research Interests

Ovarian cancer; diagnostic markers; cell-cell interactions

Educational Background

  • University of Maryland, Maryland (1980), B.S. (Biochemistry)
  • John Hopkins University, Maryland (1984), Ph.D. (Pharm and Exp. Ther.)
  • University of Minnesota, Minnesota (1988) Posdoctoral (Lab. Med and Pathol.)

Professional Background

  • Postdoctoral Fellow, Dept. Lab Medicine & Pathology, Univ. of Minnesota, 1984 - 1987
  • Research Associate, Dept. Lab Medicine & Pathology, Univ. of Minnesota, 1988 - 1990
  • Assistant Professor, Dept. Lab Medicine & Pathology, Univ. of Minnesota, 1988 - 1996
  • Assistant Professor of Biomedical Engineering, Univ. of Minnesota, 1991 - 1996
  • Director, Cancer Center Tissue Procurement Facility, Univ. of Minnesota, 1995 - 2002
  • Assoc. Professor, Dept. Lab Medicine & Pathology, Univ. of Minnesota, 1996 - 2007
  • Director, Cancer Center Tissue Procurement Facility, 2007 - present
  • Professor (tenured), Dept. Lab Medicine & Pathology, Univ. of Minnesota, 2007 - present

Professional Honors

  • Bowie Woman's Club Scholarship , University of Maryland, 1976 - 1977
  • General Honors Program, University of Maryland, 1976 - 1980
  • Dean's List Scholar, University of Maryland, 1976 - 1980
  • Award for Distinguished Undergraduate Scholarship , University of Maryland, 1979
  • Phi Kappa Phi National Honor Society, University of Maryland, 1979
  • Phi Sigma Phi National Honor Society, University of Maryland, 1979
  • Noxell Foundation Scholarship, University of Maryland, 1979 - 1980
  • Award for excellence in the field of Pharmacology, Sandoz, 1985
  • National Research Service Award, National Institutes of Health, 1986
  • Postdoctoral Fellowship Award, American Cancer Society, 1986 - 1988

Professional Memberships

  • Study Section Member: Grants-in-aid and fellowships, American Heart Association, MN Affiliate, 1991 - 1994
  • Study Section Member: Special Review Committee, NIH/NCI, to review a Program Project, 1992
  • & 1997, Study Section Member: External Referee, Study Section Member: Grants-in-aid of research for the Med. Research Council of Canada, 1992
  • Study Section Member: External Reviewer; Research scholarships for The Fonds de la recherche en sante du Quebec, 1993
  • Temporary Member; NIH, Oral Biology and Medicine Study Section, Subcommittee 2, 1998
  • Member, Special Emphasis Panel, NIH/NCI to review applications in response to RFA U01CA02-001, "Tissue and Biological Fluids of HIV-related Malignancies" , 2001
  • Scientific Reviewer for OCRP-1 Scientific Peer Review Panel, Department of Defense, U.S. Army Medical Research and Materiel Command, Congressionally Directed Medical Research Programs (CDMRP), Fiscal year 2004 Ovarian Cancer Research Program, 2004
  • Memberships in Societies: International Society for Biological and Environmental Repositories, MNBIO, National Ovarian Cancer Coalition, University of Minnesota Cancer Center

Publications

  • Betsou F, Lehmann S, Ashton G, Barnes M, Benson EE, Coppola D, DeSouza Y, Eliason J, Glazer B, Guadagni F, Harding K, Horsfall DJ, Kleeberger C, Nanni U, Prasad A, Shea K, Skubitz A, Somiari S, Gunter E. [ISBER Working Group on Biospecimen Science] Standard preanalytical coding for biospecimens: defining the sample PREanalytical code. Cancer Epidemiology Biomarkers Prevention 2010 Apr;19(4):1004-11.
  • Boylan, K.L.M., Andersen, J.D., Anderson, L.B., Higgins, L., and Skubitz, A.P.N. Quantitative proteomic analysis by iTRAQ® for the identification of candidate biomarkers in ovarian cancer serum. Proteome Science 2010 8:31-39.
  • Andersen, J.D., Boylan, K.L.M., Jemmerson, R., Geller, M.A., Misemer, B., Harrington, K.M., Weivoda, S., Witthuhn, B.A., Argenta, P., Vogel, R.I., and Skubitz, A.P.N. Leucine-rich alpha-2-glycoprotein-1 is upregulated in sera and tumors of ovarian cancer patients. Journal of Ovarian Research 2010 3:21-34.
  • DeRycke M.S., Pambuccian S.E., Gilks C.B., Kalloger S.E., Ghidouche A., Lopez M., Bliss R.L., Geller M.A., Argenta P.A., Harrington K.M., and Skubitz A.P.N. Nectin 4 overexpression in ovarian cancer tissues and serum: Potential role as a serum biomarker. American Journal of Clinical Pathology 2010 134:835-845.
  • Andersen JD, Boylan KL, Xue FS, Anderson LB, Witthuhn BA, Markowski TW, Higgins L, Skubitz AP. Identification of candidate biomarkers in ovarian cancer serum by depletion of highly abundant proteins and differential in-gel electrophoresis. Electrophoresis. 2010 Jan;31(4):599-610.
  • DeRycke MS, Andersen JD, Harrington KM, Pambuccian SE, Kalloger SE, Boylan KL, Argenta PA, Skubitz AP. S100A1 expression in ovarian and endometrial endometrioid carcinomas is a prognostic indicator of relapse-free survival. Am J Clin Pathol. 2009 Dec;132(6):846-56.
  • Betsou, F., Barnes, R., Burke, T., Coppola, D., DeSouza, Y., Eliason, J., Glazer, B., Horsfall, D., Kleeberger, C., Lehmann, S., Prasad, A., Skubitz, A., Somiari, S., Gunter E. Human biospecimen research: Experimental protocol and quality control tools [ISBER Working Group on Biospecimen Science]. Cancer Epidemiology Biomarkers Prevention 18:1017-1025.
  • Pitt, K.E. (Editor-in-Chief), Campbell, L.D., Skubitz, A.P.N., Somiari, S.B., Sexton, K.C., and Pugh, R.S. (Associate Editors) 2008 Best practices for repositories: Collection, storage, retrieval, and distribution of biological materials for research. Cell Preservation Technology 6(1):3-58.
  • Skubitz KM, Skubitz AP. Interdependency of CEACAM-1, -3, -6, and -8 induced human neutrophil adhesion to endothelial cells. J Transl Med. 2008 Dec 10;6:78.
  • Skubitz KM, Pambuccian S, Manivel JC, Skubitz AP. Identification of heterogeneity among soft tissue sarcomas by gene expression profiles from different tumors. J Transl Med. 2008 May 6;6:23.
  • Tchagang AB, Tewfik AH, DeRycke MS, Skubitz KM, Skubitz APN. Early detection of ovarian cancer using group biomarkers. Mol Cancer Ther. 2008;7:27-37.
  • Burleson KM, Boente MP, Pambuccian SE, Skubitz APN. Disaggregation and invasion of ovarian carcinoma ascites spheroids. J Transl Med. 2006;4:6.
  • Skubitz KM, Zimmerman W, Kammerer R, Pambuccian S, Skubitz APN. Differential gene expression identifies subgroups of renal cell carcinoma.  J Lab Clin Med. 2006;147:250-267.
  • Skubitz APN, Pambuccian SE, Argenta PA, Skubitz KM. Differential gene expression identifies subgroups of ovarian carcinoma. Transl Res. 2006;148:223-248.
  • Iida J, Skubitz APN, McCarthy JB, Skubitz KM. Protein kinase activity is associated with CD63 in melanoma cells. J Transl Med. 2005;3:42-50.
  • Skubitz, K.M., Cheng, E.Y., Clohisy, D.R., Thompson, R.C., and Skubitz, A. (2005) Differential gene expression in liposarcoma, lipoma, and adipose tissue. Cancer Invest. 23:105-118.
  • Hibbs K, Skubitz KM, Pambuccian S, Casey RC, Burleson KM, Oegema TR Jr, Thiele JJ, Grindle SM, Bliss R, Skubitz APN. Differential gene expression in ovarian carcinoma: Identification of potential biomarkers. Am J Path. 2004;165:397-414.
  • Skubitz, K.M. and Skubitz, A.P.N. (2004) Gene expression in aggressive fibromatosis. J. Lab. Clin. Med. 143:89-98.
  • Burleson, K.M., Casey, R.C., Skubitz, K.M., Pambuccian, S.E., Oegema, T.R., and Skubitz, A.P.N. (2004) Ovarian carcinoma ascites spheroids adhere to extracellular matrix components and mesothelial cell monolayers. Gynecologic Oncology 93:170-181.
  • Skubitz, K.M., and Skubitz, A.P.N. (2004) Characterization of sarcomas by means of gene expression. J. Lab. Clin. Med. 144:78-91.
  • Skubitz KM, Cheng EY, Clohisy DR, Thompson RC, Skubitz A.P.N. Gene expression in giant-cell tumors. J. Lab Clin Med. 2004.144:193-200.
  • Hibbs, K., Skubitz, K.M, Pambuccian, S.E., Casey, R.C., Burleson, K.M, Oegema, T.R., Thiele, J.J., Grindle, S.M., Bliss, R.L., and Skubitz, A.P.N. (2004) Differential gene expression in ovarian carcinoma: Identification of potential biomarkers. Amer. J. Pathol. 165(2):397-414.
  • Skubitz, K.M. and Skubitz, A.P.N. (2004) Role of gene expression arrays in sarcomas. Current Oncology Reports 6:309-314.
  • Skubitz, K.M., Cheng, E.Y., Clohisy, D.R., Thompson, R.C., and Skubitz, A.P.N. (2004) Gene expression in giant-cell tumors. J. Lab. Clin. Med. 144:193-200.
  • Burleson, K.M., Hansen, L.K., Skubitz, A.P.N. (2004) Ovarian carcinoma spheroids disaggregate on type I collagen and invade live human mesothelial cell monolayers. Clin. & Exper. Metast. 21:685-697.

For a complete listing of Dr. Skubitz' publications, please see the National Library of Medicine's PubMed Search (opens in a new window).


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