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  Home > About Lab Medicine & Pathology > Faculty and Staff > (John) Jeffrey McCullough, M.D.

(John) Jeffrey McCullough, M.D.

Dr. Jeffrey McCullough
Contact Information

Phone: 612-626-3272




MMC 609 Mayo
420 Delaware
Minneapolis, MN 55455


Educational Background

  • Northwestern University, Evanston, Illinois, B.A., 1959
  • Ohio State University, Columbus, Ohio, M.D., 1963
  • Vanderbilt University Hospital, Nashville, Tennessee, Intern, Department of Medicine, July 1963 - June 1964, Resident, July 1969 - June 1970
  • University of Minnesota Hospitals, Resident, Department of Laboratory Medicine, 1967 - 1969; Chief Resident 1968 - 1969
  • Executive Development Program, Kellogg Graduate School of Management, Northwestern University, Evanston, IL, August, 1982
  • National Heart, Lung, and Blood Institute, Laboratory of Molecular Hematology: Sabbatical with Dr. French Andersen, 1985 - 1986

Professional Background

  • Professor, Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, 1978 to present
  • American Red Cross Chair in Transfusion Medicine, 2003 to present
  • Director, Biomedical Engineering Institute, 2000 to present
  • Scientific Director, St. Paul Regional Red Cross Blood Service, 1992 to present
  • Trustee, American Board of Pathology, 1997 to present
    Treasurer, 2003 - 2004
    President, 2006 to present


  • Academy of Clinical Laboratory Physicians and Scientists
  • American Association for the Advancement of Science
  • American Association of Blood Banks
  • American Society for Blood and Marrow Transplantation
  • American Society for Investigative Pathology
  • American Society of Hematology
  • Biomedical Engineering Society
  • College of American Pathologists
  • International Society of Blood Transfusion
  • International Society for Cell Therapy
  • Minnesota Society of Pathologists


Clinical Pathology, Blood Banking


  • Ayyoubi MT, Konstenius T, McCullough JC, Eastlund T, Clay M, Bowman R, Rahmani AM, Riley W, McCullough J. Status of blood banking and the blood supply in Afghanistan. Transfusion. 2010 Mar;50(3):566-74.
  • McCullough J, Haley R, Clay M, Hubel A, Lindgren B, Moroff G. Long-term storage of peripheral blood stem cells frozen and stored with a conventional liquid nitrogen technique compared with cells frozen and stored in a mechanical freezer. Transfusion. 2010 Apr;50(4):808-19.
  • McCullough J, McKenna D, Kadidlo D, Maurer D, Noreen HJ, French K, Brunstein C, Wagner JE. Mislabeled units of umbilical cord blood detected by a quality assurance program at the transplantation center. Blood. 2009 Aug 20;114(8):1684-8.
  • McCullough J, Kahn J, Adamson J, Anderlini P, Benjamin R, Confer D, Eapen M, Hirsch B, Kuter D, Lazarus E, Pamphilon D, Stroncek D, Sugarman J, Wilson R. Hematopoietic growth factors--use in normal blood and stem cell donors: clinical and ethical issues. Transfusion. 2008 Sep;48(9):2008-25.
  • McKenna DH, Sumstad D, Bostrom N, Kadidlo DM, Fautsch S, McNearney S, DeWaard R, McGlave PB, Weisdorf DJ,
    Wagner JE, McCullough J, Miller JS. Good manufacturing practices production of natural killer cells for immunotherapy:
    a six year single-institution experience. Transfusion 2007; 47:520-528
  • Greeno E, McCullough J, Weisdorf D. Platelet utilization and the transfusion trigger: a prospective analysis. Transfusion
    2007; 47:201-205.
  • Riley W, Schwei M, McCullough J. The United States’ potential blood donor pool: estimating the prevalence of donor
    exclusion factors on the pool of potential donors. Transfusion 2007; 47:1180-1188
  • McCullough J. Pathogen inactivation: a new paradigm for preventing transfusion-transmitted infections. Am J Clin Path 2007;
  • McCullough J. Pathogen inactivation: a new paradigm for blood safety. Transfusion 2007; 47:2180-2184
  • McCullough J. The role of physicians in blood centers. Transfusion 2006; 46:854-861
  • Mintz PD, Bass NM, Petz LD, Steadman R, Streiff M, McCullough J, et al. Photochemically treated fresh frozen plasma for
    transfusion of patients with acquired coagulopathy of liver disease. Blood 2006; 107:3753-3760
  • McCullough J, Perkins HA, Hansen J. The National Marrow Donor Program with emphasis on the early years. Transfusion 2006;
  • Klein MA, Kadidlo D, McCullough J, McKenna DH, Burns LJ. Microbial contamination of hematopoietic stem cell products:
    incidence and clinical sequelae. Biol of Blood & Marrow Transplant. 2006; 12:1142-11-49
  • Ballen KK, Haley NR, Kurtzberg J, Lane TA, Lindgren BR, Miller JP, Newman B, McCullough J. Outcomes of 122 diverse
    adult and pediatric cord blood transplant recipients from a large cord blood bank. Transfusion 2006; 46:2063-2070
  • Murphy S, Snyder E, Cable R, Slichter SJ, Strauss RG, McCullough J, Lin JS, Corash L, Conlan MG.  Platelet dose consistency and its Effect on the number of platelet transfusions for support of thrombocytopenia: an analysis of the SPRINT trial of platelets photochemically treated with amotosalen HC1 and ultraviolet A light.  Transfusion 2006; 46:24-33.
  • McCullough J.  Transfusion Medicine (2nd ed).  Elsevier Churchill Livingstone; Philadelphia, PA, 2005; 584 pgs.
  • Askari S, Miller J, Chrysler G, McCullough J.  Impact of donor- and collection-related variables on product quality in ex-utero cord blood banking.  Transfusion 2005; 45:189-194.
  • Perez-Pujol S, Aras O, Lozano M, Cocking-Johnson D, Key NS, White JG, McCullough J, Escolar G.  Stored platelets contain residual amounts of tissue factor: evidence from studies on platelet concentrates stored for prolonged periods.  Transfusion 2005; 45:572-579.
  • Slichter SJ, Davis K, Enright H, Braine H, Gernsheimer T, Kao KJ, Kickler T, Lee E, McFarland J, McCullough J, Rodey G, Schiffer CA, Woodson R.  Factors affecting post-transfusion platelet increments, platelet refractoriness, and platelet transfusion intervals in thrombocytopenic patients.  Blood 2005 105:4106-4114.
  • McCullough J, McKenna D, Schierman T, Kadidlo D, Wagner J.  Issues in the quality of umbilical cord blood (UCB) stem cells for transplantation.  Transfusion 2005; 45:832-841.
  • McKenna DH, Kadidlo DM, Miller JS, Orchard PJ, Wagner JE, McCullough J.  The Minnesota Molecular and Cellular Therapeutics Facility: a state-of-the-art biotherapeutics engineering laboratory.  Transfusion Medicine Reviews 2005; 19:217-228.
  • Benjamin RJ, McCullough J, Mintz PD, Snyder E, Spotnitz WD, Rizzo RJ, Wages D, Lin JS, Wood L, Corash L, Conlan MG.  Therapeutic efficacy and safety of red blood cells treated with a chemical process (S-303) for pathogen inactivation: a Phase III clinical trial in cardiac surgery patients.  Transfusion 2005; 45:1730-1749.
  • Snyder E, McCullough J, Slichter SJ, Strauss RG, Lopez-Plaza I, Lin SJ, Corash L, Conlan MG, and the SPRINT Study Group.  Clinical safety of platelets photochemically-treated with amotosalen HC1 and ultraviolet A light for pathogen inactivation:  the SPRINT trial.  Transfusion 2005; 45:1864-1875.
  • Laroche V, McKenna D, Moroff G, Schierman T, Kadidlo D, McCullough J.  Cell loss and recovery in umbilical cord blood processing: a comparison of postthaw and postwash samples.  Transfusion 2005; 45:1909-1916.
  • Chrysler G, McKenna D, Schierman T, Kadidlo D, Askari S, Miller J, Clay M, McCullough J.  Cellular characteristics of cord blood and cord blood transplantation.  In:  Broxmeyer HE, ed.  Cord Blood:  Biology, Immunology, Banking, and Clinical Transplantation.  AABB Press, Bethesda, MD, 2004; 219-257.
  • McCullough J, Dodd R, Gilcher R, Murphy S, Sayers M.  White particulate matter:  Report of the ad hoc industry review group.  Transfusion 2004; 44:1112-1118.
  • McCullough J, Vesole DH, Benjamin RJ, Slichter SJ, Pineda A, Snyder E, Stadtmauer EA, Lopez-Plaza I, Coutre S, Strauss RG, Goodnough LT, Friday JL, Raife T, Cable R, Murphy S, Howard F, Davis K, Lin JS, Metzel P, Corash L, Koutsoukos A, Lin L, Buchholz DH, Conlan MG.  Therapeutic efficacy and safety of platelets treated with a photochemical process for pathogen inactivation: The SPRINT trial.  Blood 2004; 104:1534-1541.
  • Laroche V, Eastlund DT, McCullough J.  Review: immunohematologic aspects of allogeneic hematopoietic progenitor cell transplantation.  Immunohematology 2004; 20:217-225.


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